Magento 2 Table Rate Shipping Extension involves configuring tax settings and customizing invoice templates. Start by enabling tax calculations in the Magento 2 backend and setting up tax rules as per the regions you operate in. Then, modify the invoice PDF template to include relevant tax details, such as tax rate and total tax amount, alongside the table rate shipping cost. With Magento 2 Table Rate, this customization ensures that customers see a clear breakdown of charges on their invoices.